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Godan verb with 'su' ending, transitive verb
to use completely, to use up, to exhaust
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毎晩飲み歩いてばかりいたら、奥さんに愛想尽かされるぞ。
If you stay out drinking every night, your wife is going to leave you.
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Godan verb with 'su' ending, transitive verb
to exhaust someone's civility, to give up (on someone)